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1

Prevalence of Trachoma in Unity State, South Sudan: Results from a Large-Scale Population-Based Survey and Potential Implications for Further Surveys

Edwards, Tansy, Smith, Jennifer, Sturrock, Hugh J. W., Kur, Lucia W., Sabasio, Anthony, Finn, Timothy P., Lado, Mounir, Haddad, Danny, Kolaczinski, Jan H., Ngondi, Jeremiah M.

Journal:

PLoS Neglected Tropical Diseases

Year:

2012

Language:

english

File:

PDF, 322 KB

english, 2012

2

The Design and Development of a Potent and Selective Novel Diprolyl Derivative That Binds to the N-Domain of Angiotensin-I Converting Enzyme

Fienberg, Stephen, Cozier, Gyles E., Acharya, K. Ravi, Chibale, Kelly, Sturrock, Edward D.

Journal:

Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 3.31 MB

english, 2018

3

Sialylation of urinary prothrombin fragment 1 is implicated as a contributory factor in the risk of calcium oxalate kidney stone formation

Dawn Webber, Catherine M. Radcliffe, Louise Royle, Gemma Tobiasen, Anthony H. Merry, Allen L. Rodgers, Edward D. Sturrock, Mark R. Wormald, David J. Harvey, Raymond A. Dwek, Pauline M. Rudd

Journal:

Year:

2006

Language:

english

File:

PDF, 430 KB

english, 2006

4

Synthesis and molecular modeling of a lisinopril–tryptophan analogue inhibitor of angiotensin I-converting enzyme

Aloysius T. Nchinda, Kelly Chibale, Pierre Redelinghuys, Edward D. Sturrock

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 151 KB

english, 2006

5

Ace revisited: A new target for structure-based drug design

Acharya, K. Ravi, Sturrock, Edward D., Riordan, James F., Ehlers, Mario R. W.

Journal:

Nature Reviews Drug Discovery

Year:

2003

Language:

english

File:

PDF, 382 KB

english, 2003

6

Erythroblast iron metabolism and serum soluble transferrin receptor values in the anemia of rheumatoid arthritis

Edward J. Fitzsimons, Tracey Houston, Robin Munro, Roger D. Sturrock, Anthony B. J. Speekenbrink, Jeremy H. Brock

Journal:

Arthritis Care & Research

Year:

2002

Language:

english

File:

PDF, 80 KB

english, 2002

7

Synthesis of novel keto-ACE analogues as domain-selective angiotensin I-converting enzyme inhibitors

Aloysius T. Nchinda, Kelly Chibale, Pierre Redelinghuys, Edward D. Sturrock

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 108 KB

english, 2006

8

Soluble LDL-R are formed by cell surface cleavage in response to phorbol esters

Michael J. Begg, Edward D. Sturrock, Deneys R. van der Westhuyzen

Journal:

Year:

2004

Language:

english

File:

PDF, 353 KB

english, 2004

9

Inhibition of calcium oxalate crystallization by commercial human serum albumin and human urinary albumin isolated from two different race groups: evidence for possible molecular differences

Allen L. Rodgers, Priscilla D. Mensah, Sylva L. Schwager, Edward D. Sturrock

Journal:

Year:

2006

Language:

english

File:

PDF, 188 KB

english, 2006

10

Glycosylation of prothrombin fragment 1 governs calcium oxalate crystal nucleation and aggregation, but not crystal growth

Dawn Webber, Allen L. Rodgers, Edward D. Sturrock

Journal:

Year:

2007

Language:

english

File:

PDF, 519 KB

english, 2007

11

A study of crystal matrix extract and urinary prothrombin fragment 1 from a stone-prone and stone-free population

Dawn Durrbaum, Allen L. Rodgers, Edward D. Sturrock

Journal:

Year:

2001

Language:

english

File:

PDF, 347 KB

english, 2001

12

Effects of biotic disturbances on forest carbon cycling in the United States and Canada

Jeffrey A. Hicke, Craig D. Allen, Ankur R. Desai, Michael C. Dietze, Ronald J. Hall, Edward H. (Ted) Hogg, Daniel M. Kashian, David Moore, Kenneth F. Raffa, Rona N. Sturrock, James Vogelmann

Journal:

Global Change Biology

Year:

2012

Language:

english

File:

PDF, 683 KB

english, 2012

13

The role of ADAM10 and ADAM17 in the ectodomain shedding of angiotensin converting enzyme and the amyloid precursor protein

Tobias M. J. Allinson, Edward T. Parkin, Thomas P. Condon, Sylva L. U. Schwager, Edward D. Sturrock, Anthony J. Turner, Nigel M. Hooper

Journal:

Year:

2004

Language:

english

File:

PDF, 256 KB

english, 2004

14

Structural characterization of angiotensin I-converting enzyme in complex with a selenium analogue of captopril

Mohd Akif, Geoffrey Masuyer, Sylva L. U. Schwager, Bhaskar J. Bhuyan, Govindasamy Mugesh, R. Elwyn Isaac, Edward D. Sturrock, K. Ravi Acharya

Journal:

Year:

2011

Language:

english

File:

PDF, 400 KB

english, 2011

15

Crystal structure of the human angiotensin-converting enzyme–lisinopril complex

Natesh, Ramanathan, Schwager, Sylva L. U., Sturrock, Edward D., Acharya, K. Ravi

Journal:

Year:

2003

Language:

english

File:

PDF, 863 KB

english, 2003

16

A high-throughput fluorimetric assay for angiotensin I-converting enzyme

Schwager, Sylva L, Carmona, Adriana K, Sturrock, Edward D

Journal:

Nature Protocols

Year:

2006

Language:

english

File:

PDF, 142 KB

english, 2006

17

A continuous fluorescence resonance energy transfer angiotensin I-converting enzyme assay

Carmona, Adriana K, Schwager, Sylva L, Juliano, Maria A, Juliano, Luiz, Sturrock, Edward D

Journal:

Nature Protocols

Year:

2006

Language:

english

File:

PDF, 225 KB

english, 2006

18

Development of Domain-Selective Angiotensin I-Converting Enzyme Inhibitors

PIERRE REDELINGHUYS, ALOYSIUS T. NCHINDA, EDWARD D. STURROCK

Journal:

Annals of the New York Academy of Sciences

Year:

2005

Language:

english

File:

PDF, 941 KB

english, 2005

19

Cloning and Expression of a Functionally Active Truncated N-Glycosylated KSHV ORF4/KCP/Kaposica in the Methylotrophic Yeast Pichia pastoris

NEUZA A. GOMES PEREIRA, MARIA A. JULIANO, ADRIANA K. CARMONA, EDWARD D. STURROCK, GIRISH J. KOTWAL

Journal:

Annals of the New York Academy of Sciences

Year:

2005

Language:

english

File:

PDF, 3.90 MB

english, 2005

20

Catalytic properties of recombinant dipeptidyl carboxypeptidase from Escherichia coli: a comparative study with angiotensin I-converting enzyme

Cunha, Carlos Eduardo L., de Fátima Magliarelli, Helena, Paschoalin, Thaysa, Nchinda, Aloysius T., Lima, Jackson C., Juliano, Maria A., Paiva, Paulo B., Sturrock, Edward D., Travassos, Luiz R., Carmon

Journal:

Biological Chemistry

Year:

2009

Language:

english

File:

PDF, 248 KB

english, 2009

21

Angiotensin I-converting enzyme inhibitor peptides derived from the endostatin-containing NC1 fragment of human collagen XVIII

Cezari, Maria Helena S., Juliano, Maria A., Sturrock, Edward D., Carmona, Adriana K., Juliano, Luiz, Farias, Shirley L., Sabatini, Regiane A., Sampaio, Tatiana C., Hirata, Izaura Y.

Journal:

Biological Chemistry

Year:

2006

Language:

english

File:

PDF, 97 KB

english, 2006

22

Limited Proteolysis of Human Kidney Angiotensin-Converting Enzyme and Generation of Catalytically Active N- and C-Terminal Domains

Edward D. Sturrock, Sergei M. Danilov, James F. Riordan

Journal:

Biochemical and Biophysical Research Communications

Year:

1997

Language:

english

File:

PDF, 126 KB

english, 1997

23

Limited Proteolysis of Human Kidney Angiotensin-Converting Enzyme and Generation of Catalytically Active N- and C-Terminal Domains: Volume 236, Number 1 (1997), pages 16–19:

Edward D. Sturrock, Sergei M. Danilov, James F. Riordan

Journal:

Biochemical and Biophysical Research Communications

Year:

1997

File:

PDF, 17 KB

1997

24

Deletion of the cytoplasmic domain increases basal shedding of angiotensin-converting enzyme

Anthony J Chubb, Sylva L.U Schwager, Elizabeth van der Merwe, Mario R.W Ehlers, Edward D Sturrock

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 234 KB

english, 2004

25

Crystal structure of a phosphonotripeptide K-26 in complex with angiotensin converting enzyme homologue (AnCE) from Drosophila melanogaster

Mohd Akif, Ioanna Ntai, Edward D. Sturrock, R. Elwyn Isaac, Brian O. Bachmann, K. Ravi Acharya

Journal:

Biochemical and Biophysical Research Communications

Year:

2010

Language:

english

File:

PDF, 729 KB

english, 2010

26

Characterization of the first angiotensin-converting like enzyme in bacteria: Ancestor ACE is already active

Guillaume Rivière, Annie Michaud, Hazel R. Corradi, Edward D. Sturrock, K. Ravi Acharya, Virginie Cogez, Jean-Pierre Bohin, Didier Vieau, Pierre Corvol

Journal:

Year:

2007

Language:

english

File:

PDF, 779 KB

english, 2007

27

Crystal Structure of the N Domain of Human Somatic Angiotensin I-converting Enzyme Provides a Structural Basis for Domain-specific Inhibitor Design

Hazel R. Corradi, Sylva L.U. Schwager, Aloysius T. Nchinda, Edward D. Sturrock, K. Ravi Acharya

Journal:

Journal of Molecular Biology

Year:

2006

Language:

english

File:

PDF, 774 KB

english, 2006

28

High-Resolution Crystal Structures of Drosophila melanogaster Angiotensin-Converting Enzyme in Complex with Novel Inhibitors and Antihypertensive Drugs

Mohd Akif, Dimitris Georgiadis, Aman Mahajan, Vincent Dive, Edward D. Sturrock, R. Elwyn Isaac, K. Ravi Acharya

Journal:

Journal of Molecular Biology

Year:

2010

Language:

english

File:

PDF, 2.34 MB

english, 2010

29

Defining the boundaries of the testis angiotensin I-converting enzyme ectodomain

Anthony J Chubb, Sylva L.U Schwager, Zenda L Woodman, Mario R.W Ehlers, Edward D Sturrock

Journal:

Biochemical and Biophysical Research Communications

Year:

2002

Language:

english

File:

PDF, 454 KB

english, 2002

30

The chronic anaemia of rheumatoid arthritis: iron banking or blocking?

Edward J Fitzsimons, Roger D Sturrock

Journal:

Year:

2002

Language:

english

File:

PDF, 59 KB

english, 2002

31

Homologous substitution of ACE C-domain regions with N-domain sequences: effect on processing, shedding, and catalytic properties

Woodman, Zenda L., Schwager, Sylva L.U., Redelinghuys, Pierre, Chubb, Anthony J., van der Merwe, Elizabeth L., Ehlers, Mario R.W., Sturrock, Edward D.

Journal:

Biological Chemistry

Year:

2006

Language:

english

File:

PDF, 279 KB

english, 2006

32

Characterization of angiotensin I-converting enzyme N-domain selectivity using positional-scanning combinatorial libraries of fluorescence resonance energy transfer peptides

Bersanetti, Patrícia A., Sabatini, Regiane A., Matos, Beatriz S., Douglas, Ross G., Nchinda, Aloysius, Juliano, Maria A., Pesquero, João Bosco, Sturrock, Edward D., Carmona, Adriana K.

Journal:

Biological Chemistry

Year:

2012

Language:

english

File:

PDF, 605 KB

english, 2012

33

Structural basis of peptide recognition by the angiotensin-1 converting enzyme homologue AnCE from Drosophila melanogaster

Akif, Mohd, Masuyer, Geoffrey, Bingham, Richard J., Sturrock, Edward D., Isaac, R. Elwyn, Acharya, K. Ravi

Journal:

Year:

2012

Language:

english

File:

PDF, 750 KB

english, 2012

34

Molecular recognition and regulation of human angiotensin-I converting enzyme (ACE) activity by natural inhibitory peptides

Masuyer, Geoffrey, Schwager, Sylva L. U., Sturrock, Edward D., Isaac, R. Elwyn, Acharya, K. Ravi

Journal:

Scientific Reports

Year:

2012

Language:

english

File:

PDF, 2.08 MB

english, 2012

35

Handbook of Proteolytic Enzymes || Peptidyl-Dipeptidase A/Angiotensin I-Converting Enzyme

Sturrock, Edward D.

Year:

2013

Language:

english

File:

PDF, 774 KB

english, 2013

36

Angiotensin-Converting Enzyme-2 (ACE2): Comparative Modeling of the Active Site, Specificity Requirements, and Chloride Dependence †

Guy, Jodie L., Jackson, Richard M., Acharya, K. Ravi, Sturrock, Edward D., Hooper, Nigel M., Turner, Anthony J.

Journal:

Year:

2003

Language:

english

File:

PDF, 293 KB

english, 2003

37

Antifibrotic peptide N -acetyl-Ser-Asp-Lys-Pro (Ac-SDKP): Opportunities for angiotensin-converting enzyme inhibitor design

Douglas, Ross G, Ehlers, Mario R, Sturrock, Edward D

Journal:

Clinical and Experimental Pharmacology and Physiology

Year:

2013

Language:

english

File:

PDF, 260 KB

english, 2013

38

New ketomethylene inhibitor analogues: synthesis and assessment of structural determinants for N-domain selective inhibition of angiotensin-converting enzyme

Sharma, Rajni K., Douglas, Ross G., Louw, Stefan, Chibale, Kelly, Sturrock, Edward D.

Journal:

Biological Chemistry

Year:

2012

Language:

english

File:

PDF, 1.41 MB

english, 2012

39

Structural Details on the Binding of Antihypertensive Drugs Captopril and Enalaprilat to Human Testicular Angiotensin I-Converting Enzyme †,‡

Natesh, Ramanathan, Schwager, Sylva L. U., Evans, Hazel R., Sturrock, Edward D., Acharya, K. Ravi

Journal:

Year:

2004

Language:

english

File:

PDF, 349 KB

english, 2004

40

Simulated Interactions between Angiotensin-Converting Enzyme and Substrate Gonadotropin-Releasing Hormone: Novel Insights into Domain Selectivity †

Papakyriakou, Athanasios, Spyroulias, Georgios A., Sturrock, Edward D., Manessi-Zoupa, Evy, Cordopatis, Paul

Journal:

Year:

2007

Language:

english

File:

PDF, 646 KB

english, 2007

41

Pharmacokinetic evaluation of lisinopril-tryptophan, a novel C-domain ACE inhibitor

Denti, Paolo, Sharp, Sarah-Kate, Kröger, Wendy L., Schwager, Sylva L., Mahajan, Aman, Njoroge, Mathew, Gibhard, Liezl, Smit, Ian, Chibale, Kelly, Wiesner, Lubbe, Sturrock, Edward D., Davies, Neil H.

Journal:

European Journal of Pharmaceutical Sciences

Year:

2014

Language:

english

File:

PDF, 1.10 MB

english, 2014

42

Interkingdom Pharmacology of Angiotensin-I Converting Enzyme Inhibitor Phosphonates Produced by Actinomycetes

Kramer, Glenna J., Mohd, Akif, Schwager, Sylva L. U., Masuyer, Geoffrey, Acharya, K. Ravi, Sturrock, Edward D., Bachmann, Brian O.

Journal:

ACS Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 1.94 MB

english, 2014

43

Crystal structures of highly specific phosphinic tripeptide enantiomers in complex with the angiotensin-I converting enzyme

Masuyer, Geoffrey, Akif, Mohd, Czarny, Bertrand, Beau, Fabrice, Schwager, Sylva L. U., Sturrock, Edward D., Isaac, R. Elwyn, Dive, Vincent, Acharya, K. Ravi

Journal:

Year:

2014

Language:

english

File:

PDF, 672 KB

english, 2014

44

A Computational Approach to the Study of the Binding Mode of Dual ACE/NEP Inhibitors

Dimitropoulos, Nikolaos, Papakyriakou, Athanasios, Dalkas, Georgios A., Sturrock, Edward D., Spyroulias, Georgios A.

Journal:

Journal of Chemical Information and Modeling

Year:

2010

Language:

english

File:

PDF, 3.95 MB

english, 2010

45

The Structure of Testis Angiotensin-Converting Enzyme in Complex with the C Domain-Specific Inhibitor RXPA380 †,‡

Corradi, Hazel R., Chitapi, Itai, Sewell, B. Trevor, Georgiadis, Dimitris, Dive, Vincent, Sturrock, Edward D., Acharya, K. Ravi

Journal:

Year:

2007

Language:

english

File:

PDF, 489 KB

english, 2007

46

Mapping of Conformational mAb Epitopes to the C Domain of Human Angiotensin I-Converting Enzyme

Naperova, Irina A., Balyasnikova, Irina V., Schwartz, David E., Watermeyer, Jean, Sturrock, Edward D., Kost, Olga A., Danilov, Sergei M.

Journal:

Journal of Proteome Research

Year:

2008

Language:

english

File:

PDF, 8.93 MB

english, 2008

47

Phorbol Ester-Induced Juxtamembrane Cleavage of Angiotensin-Converting Enzyme Is Not Inhibited by a Stalk Containing Intrachain Disulfides †

Schwager, Sylva L. U., Chubb, Anthony J., Scholle, Renate R., Brandt, Wolf F., Eckerskorn, Christoph, Sturrock, Edward D., Ehlers, Mario R. W.

Journal:

Year:

1998

Language:

english

File:

PDF, 128 KB

english, 1998

48

Localization of an N-Domain Region of Angiotensin-Converting Enzyme Involved in the Regulation of Ectodomain Shedding Using Monoclonal Antibodies

Balyasnikova, Irina V., Woodman, Zenda L., Albrecht, Ronald F., Natesh, Ramanathan, Acharya, K. Ravi, Sturrock, Edward D., Danilov, Sergei M.

Journal:

Journal of Proteome Research

Year:

2005

Language:

english

File:

PDF, 589 KB

english, 2005

49

Cleavage of Disulfide-Bridged Stalk Domains during Shedding of Angiotensin-Converting Enzyme Occurs at Multiple Juxtamembrane Sites †

Schwager, Sylva L. U., Chubb, Anthony J., Woodman, Zenda L., Yan, Lisa, Mentele, Reinhard, Ehlers, Mario R. W., Sturrock, Edward D.

Journal:

Year:

2001

Language:

english

File:

PDF, 214 KB

english, 2001

50

Fine Epitope Mapping of Monoclonal Antibody 5F1 Reveals Anticatalytic Activity toward the N Domain of Human Angiotensin-Converting Enzyme †

Danilov, Sergei M., Watermeyer, Jean M., Balyasnikova, Irina V., Gordon, Kerry, Kugaevskaya, Elena V., Elisseeva, Yulia E., Albrecht, Ronald F., Sturrock, Edward D.

Journal:

Year:

2007

Language:

english

File:

PDF, 972 KB

english, 2007

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